Cutaneous reactions to bedbug bites can vary widely and are easily confused with other conditions (Table 1).15–19 A typical lesion is a 2- to 20-mm, pruritic, erythematous maculopapule with a central hemorrhagic crust or vesicle.5,8 Macules, papules, wheals (Figure 3), vesicles, bullae, and nodules have all been reported,20 as have asymptomatic lesions with a barely visible punctum as the only evidence of a bite.8 Bites vary in number and are preferentially distributed in unclothed areas (e.g., face, neck, extremities). Unlike many other arthropod and insect bites, bedbug bites are rarely located in the popliteal fossae or axillae.21 Lesions can be noticeable immediately when waking up or several days later, with the reaction often progressing from delayed to immediate with subsequent exposures22–26  (Table 2). The classic bedbug rash is referred to as “breakfast, lunch, and dinner” because it commonly presents as several bites in a row or cluster 20 (Figure 4).
Bed bug bites do not typically require treatment. It is best to clean the bite site(s) with soap and water and avoid scratching so as to prevent secondary infection. Progressive swelling, warmth, tenderness and sometimes (albeit rarely) fever may be signs of secondary infection, which should be managed with antibiotics as appropriate. Much more common are complaints of itching. For how to treat bed bug bites that cause severe itching, topical steroid creams or oral antihistamines may offer relief from itching and thus decrease the risk of infecting the bite site.
Wash all the clothing that you brought home in a washing machine. Even clothes that you didn't wear must be washed in hot water. If you cannot wash something in a washing machine, you can either place it in a hot dryer or seal the items in a plastic garbage bag. If you seal items in a  garbage bag, leave the bag securely closed in an extremely cold or hot place for a few months.

Spray all baseboards, loose plaster, behind bed frames and headboards, beneath beds and furniture, and bedsprings and bed frames. Do not apply to furniture surfaces or mattresses where people will be laying or sitting unless using a product labeled for that type of treatment. Infested bedding should not be treated, but should be removed, placed in sealed plastic bags, and taken for laundering and drying at high temperature.
Bed bugs typically feed at night when we are sleeping. Even though these pests commonly feed for 5 minutes, the bite itself is painless and usually goes undetected at the time. In fact, bed bugs inject an anticoagulant (a blood thinner) as they feed, which makes feeding easier for the bed bug and also less detectable to you. Although you may not see the bed bugs, or feel their bites, they know when you are around. Bed bugs are attracted to warmth and carbon dioxide. So, if you are alive, warm, and breathing - then you are broadcasting loudly and clearly to all nearby bed bugs that "dinner is served!"
The significant resurgence of bedbugs in the past decade has been attributed to pesticide resistance, more frequent travel, lack of public awareness, and inadequate pest control programs. Bedbugs are obligate blood parasites (insect family Cimicidae). They can withstand a large range of temperatures but are attracted to warmth and carbon dioxide. They typically feed just before dawn. Cutaneous reactions to bedbug bites can include macules, papules, wheals, vesicles, bullae, and nodules. Bites may be confused with other skin conditions. Bedbug bite reactions are typically self-limited and resolve within one to two weeks without treatment. Bedbug infestation may cause significant psychological distress. The diagnosis of a bedbug infestation is based on history, appearance of bites, and inspection of sleeping quarters. Although there is no evidence that bedbugs transmit disease, systemic reactions may include asthma, angioedema, generalized urticaria, iron deficiency anemia, and, rarely, anaphylaxis. An integrated pest management strategy should be employed to eliminate infestation. Tactics include vacuuming, heat or cold treatment, trapping devices, and pesticides.
Bedbugs are small, flat, wingless insects with six legs that, like mosquitoes, feed on blood from animals or people. They range in color from almost white to brown, but they turn rusty red after feeding. The common bedbug doesn't grow much longer than 0.2 inches (0.5 centimeters) and can be seen by the naked eye to the astute observer.  Bedbugs get their name because they like to hide in bedding and mattresses.
Thank you all for the advice I’m seeing on here. Hydrocortisone was doing nothing for these bites. I have a high tolerance for pain but these bites really made me want to cry. I tried the Veeno Oatmeal bath, Witch Hazel and the Aloe Vera and this is when I began to get relief. These bites were very uncomfortable. I still itch a little but the swelling has gone down tremendously. I keep the Aloe Vera and witch hazel handy for the itching.
Hey Jessica! Sounds like bed bug bites to me but don’t stress, although bed bugs are known to travel with you from other locations its not a guarantee that they always do. I recommend giving all your clothing a hot wash when you get back home (and your travel bags) and to inspect your bed for signs of their presence. As a precautionary measure, you can put DE under your sheets for a day or two and that will kill any pests that are hiding there. Good luck
Bed bugs remain a problematic pest across the United States, beyond just bed bug bites. In fact, one out of five Americans has  had a bed bug infestation in their home or knows someone who has encountered bed bugs. Reflecting the increasing problem with bed bugs,  a survey of pest management professionals found that prior to 2000 only 25 percent had encountered bed bug infestations, but in 2013 an amazing 99.6 percent of U.S. based professional pest management companies encountered bed bug infestations. Bed bugs are found in places beyond homes and hotels, such as hospitals, schools, doctors' offices, public transportation, college dorms, day cares, offices and any other places where humans live or gather.

My husband returned from a Military Deployment…and brought bed bugs home with him. The day after we realized we had them, an exterminator that specializes in Bed Bugs came to our house and sprayed. They scheduled themselves to come back in 14 days to spray again (to kill the new bugs that hatch after the initial spray). We were old the spray would kill all the adults and babies…and the second spray would get the new hatchlings. 3 days after the initial spray, we started seeing adult bugs again!


Just came back from a hotel stay, have one VERY itchy bite on my wrist. I don’t know for sure that it is a bed bug bite butI haven’t unpacked my bags yet, so hopefully everything is safe. Right now I have an aloe and lidocaine gel over the bite, but when I get home I may try soaking it in tea bath. the tannin in black tea can also help with itching and swelling.
Hello! I am not sure if we have bed bugs or not. It seems like I am the only one getting bit. We co-sleep with our children and neither of them have signs of any kind of bites. I wake up with bite marks underneath my breasts and sometimes behind my knees. The bites itch for only a few minutes and disappear a few minutes after. We have looked through our mattress and have found no signs of anything. No blood smears nor any fecal matter. Could my bites be caused by something else.
But the bites will look different from person to person, and some people won’t develop any reaction whatsoever. “The same bedbug could bite two different people and one could have no reaction at all and the other can have an extreme reaction with a swollen arm or itchy rash,” says Eric Braun, a board-certified entomologist and business manager for the national pest control company Rentokil Steritech, who is based in Redding, Pennsylvania. Some people end up developing a rash that looks like eczema. (5)
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