If you know that you have the bugs. Get sealing covers the kind that encloses completely, one for the mattress and one for the box spring. That will trap those critters inside and they will eventually die in there. Next you will need to decide of what combination of treatments you wish to use. Its a job that you will have to keep up with for some time. Do your research online first.

Español: tratar las picaduras de chinches, Deutsch: Bettwanzenbisse behandeln, Português: Tratar Picadas de Percevejos, Italiano: Trattare le Punture delle Cimici da Letto, Français: traiter des piqures de punaises de lit, Русский: лечить укусы клопов, 中文: 应对床虱叮咬, Nederlands: Bedwantsbeten behandelen, Čeština: Jak léčit štípance od štěnic, Bahasa Indonesia: Mengobati Gigitan Kutu Ranjang, Tiếng Việt: Trị Vết cắn Bọ rệp, 日本語: トコジラミの刺し跡を治療する, العربية: معالجة لدغات البقّ المنزلي, 한국어: 빈대에 물린 상처를 치료하는 법, ไทย: รักษารอยตัวเรือดกัด


Bed bugs can exist singly, but tend to congregate once established. Although strictly parasitic, they spend only a tiny fraction of their lifecycles physically attached to hosts. Once a bed bug finishes feeding, it relocates to a place close to a known host, commonly in or near beds or couches in clusters of adults, juveniles, and eggs—which entomologists call harborage areas or simply harborages to which the insect returns after future feedings by following chemical trails. These places can vary greatly in format, including luggage, inside of vehicles, within furniture, among bedside clutter—even inside electrical sockets and nearby laptop computers. Bed bugs may also nest near animals that have nested within a dwelling, such as bats, birds,[22] or rodents. They are also capable of surviving on domestic cats and dogs, though humans are the preferred host of C. lectularius.[25]
Blood spots found on one’s sheets, bites and the presence of bed bug feces and cast skins are some of the indications of a bed bug infestation. Bites are commonly found on the parts of the body that are more likely to be exposed to bed bugs during sleep – the hands, neck, face, shoulders, legs and arms. While not always the case, bed bug bites are often grouped together in a small area and at times may occur in a line or a zigzag pattern. Bites normally look like small, flat or raised areas that may become inflamed, itchy, red or blistered. Bed bug bite reactions don’t always appear immediately after you’re bitten and may take a few days to begin causing symptoms. However, not everyone reacts to bed bug bites in the same manner.
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