Cutaneous reactions to bedbug bites can vary widely and are easily confused with other conditions (Table 1).15–19 A typical lesion is a 2- to 20-mm, pruritic, erythematous maculopapule with a central hemorrhagic crust or vesicle.5,8 Macules, papules, wheals (Figure 3), vesicles, bullae, and nodules have all been reported,20 as have asymptomatic lesions with a barely visible punctum as the only evidence of a bite.8 Bites vary in number and are preferentially distributed in unclothed areas (e.g., face, neck, extremities). Unlike many other arthropod and insect bites, bedbug bites are rarely located in the popliteal fossae or axillae.21 Lesions can be noticeable immediately when waking up or several days later, with the reaction often progressing from delayed to immediate with subsequent exposures22–26  (Table 2). The classic bedbug rash is referred to as “breakfast, lunch, and dinner” because it commonly presents as several bites in a row or cluster 20 (Figure 4).


Bed bugs are challenging to eradicate. Since they can hide in so many places, inspections must be thorough and elimination is not always a certainty. Whenever resources allow, it’s prudent to enlist the services of a professional. Experienced pest controllers know where to look for bed bugs, and have an assortment of tools at their disposal. Nonetheless, owners and occupants can assist the professional in several important ways. Affording access to all living areas is crucial, and excess clutter will need to be removed. Belongings strewn about rooms offer many places for the bugs to hide, and impede inspection and treatment. Since bed bugs can disperse throughout a building, it often will be necessary to inspect adjoining rooms and apartments as well. 
About a week ago my son bought me a sectional sofa at a yard sale and by the 3rd day my grand daughter had more than 100 bites all over her arms, legs and back. I told my son that it was chicken pox because she got so full of them by the next day again, until i got up the next morning with my legs, back and arms filled with the same bites…. for my luck the sofa was loaded with the unwanted bed bugs and now they were all over my home. This is the worst itching ever not to mention the frustration when people see you with all the bite marks and they see you like you have something contagious . I threw the sofa out and found a spray called “Rest Easy bed bug repel” ($10.00) and a powder (Diatomaceous Earth) ($10.00) and sprayed all the mattress in the house along with the powder and washed EVERYTHING with hot water. I think they are gone now. I bought Calamine lotion, benadryl anti itch cream, and cortisone but the only way that my itching started to feel better was with “Gold Bond max relief cream.
Avoidance is the best means of preventing bedbug infestation.8 While traveling, sleeping quarters and bedding should be closely inspected for signs of bedbugs. Suitcases should be placed on metal racks away from walls and furniture. Frequent travelers might consider obtaining a portable heating unit for luggage and clothing (e.g., Packtite) as an additional precaution. Items at yard sales and secondhand stores should also be carefully examined before purchase.8  All potentially infested items should be sorted and sealed in plastic bags and removed only when ready to be disinfested (see Table 36 for instructions regarding effective care of infested items). Wearing long-sleeved nightclothes can minimize exposed skin, and although insect repellants have not been shown to be reliably effective, oil of lemon eucalyptus or diethyltoluamide (DEET) might help deter bites.44,45

We had an exterminator check our mattress and he found old dried remains of a bed bug. Never had any bites. Sometimes I will get a small welt that itches for a few minutes then nothing. I have checked the bed ten thousand times and never saw anything. Please don’t say we have bed bugs. I’m losing my mind. Am a senior so if there’s anything I can use that’s household and low cost please let me know. Thank you.

Many news reports in recent years have focused on the discovery of bedbugs and their health effects (even in upscale five-star hotels), and a number of lawsuits have been filed by guests of fashionable hotels who awoke to find hundreds of bedbug bites covering their skin. Searching on travel-review web sites regularly reveals information and even photos confirming the presence of bedbugs in numerous hotels.
My husband and I recently stayed at a Scottish Inn, off I-75 in Florida, on our way back from NJ. We needed a room on the first floor. The only thing they had was a $32.00 room + tax. Since we were tired from driving, we took it. During the night, I woke up and I felt like something had bitten me. When we got up to get ready to leave, I noticed both my arms, left leg, one on my face, left ear and one bite on my neck had been bitten. I immediately took a hot bath, but I still can’t stop itching. I’ve never had bed bug bites before so I visited this site. I definitely will be trying the baking soda and water mix. My husband has two bites on his arm, but they’re not as bad as mine. He thinks he received them at the prior motel we stayed at.
A variety of low-odor sprays, dusts, and aerosol insecticides help with bed bug control. People must apply these pesticides to all areas where the bugs are observed as well as hiding places or spaces where they may crawl. The pest control company can help you determine if an infested mattress can be disinfected or must be discarded. Since beds cannot readily be treated with insecticides, it's often necessary to discard infested mattresses and beds.

I have various skin lesions which might or might not be bed-bug bites–small, raised, sometimes red, sometimes itchy. The problem is I live right next door to a large park and get all kinds of insects in summer, may small enough to get through my window-screen. Also, I have Parkinson’s disease, and the meds I take for it can produce hives and itching as a side-effect. And, my bedding and mattress are all dark colored, so I likely would not see fecal stains or shed bed-bug skins.

Wash the bites with soap and water. Wash the area with mild soap and water; use a bar of soap and enough water to wet surface of your hands. Work the soap in your hands into thick, soapy lather. Rub the lather over the affected area liberally. Repeat until the entire area is covered. Leave on and do not rinse. Allow the soap lather to dry over the bitten areas. You should experience immediate relief from itching.[5]

Recently I went to Dubai, I stayed at my husband’s rental furnished flat. The next morning I was covered with bites. Immediately I knew its big bites but don’t know it’s bed bugs until I google search online a few days. I was so allergic to the bites & can’t stop scratching them. At last I went to a local pharmacy and got this ‘Fenistil Gel’ AKA Dimetindene maleate. it works really well. My bites stop itching, swelling reduced. Some bites I need to applied the gel 1-2 times a day then it stopped bothering me. The only problem now is the marks never go away. :(
Have you tried the hot-water cure? It’s old fashioned but works for all kinds of bites (mosquitoes, fleas, BB, sand fleas and poison ivy and oak and also for bee and wasp strings but not spider or venomous bites) . My doctor told me about it when I was pregnant and had got bitten by sand fleas. You take a very hot shower, as you put the water hotter and hotter, the itching increases dramatically. You do this until it starts burning SLIGHTLY, BE CAREFUL NOT TO BURN YOURSELF!
Bites on dogs and cats will look much like bites on people, and the pet owner may actually suspect a mosquito or flea bit the pet. As with people, bed bugs do not stay on pets, but return to a protected harborage site after feeding. In addition to bites, the presence of the bug’s feces, cast skins and the animal’s irritation at night are also indicators of bed bugs biting pets. Therefore, one of the best things to do is inspect the pet’s bedding and frequently groom the animal while being vigilant for the telltale signs of bed bug presence.
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